{"dataset":{"id":"44800","dataset_id":"on006902","name":"Profound neuronal differences during Exercise-Induced Hypoalgesia between athletes and non-athletes revealed by functional near-infrared spectroscopy","description":"This functional near-infrared spectroscopy (fNIRS) dataset investigates neuronal mechanisms underlying exercise-induced hypoalgesia in endurance athletes versus non-athletes. Twenty-two athletes and twenty non-athletes performed high-intensity interval training (HIIT) while brain oxygenation was monitored across pain-processing regions including the prefrontal cortex, sensorimotor cortices, and posterior parietal cortex. The study reveals distinct neural activation patterns and pain reduction responses between groups, with athletes demonstrating greater oxyhemoglobin increases in the posterior parietal cortex during exercise and significant post-HIIT decreases in pain perception correlated with prefrontal cortex deactivation.","owner_user_id":15,"status":"active","github_repo":"nemarDatasets/on006902","concept_doi":"10.82901/nemar.on006902","latest_version_doi":"10.82901/nemar.on006902.v1.0.0","created_at":"2026-06-18 23:07:58","updated_at":"2026-07-10 23:08:21","zenodo_concept_id":null,"is_sandbox":0,"visibility":"public","ezid_status":"public","enrichment_json":"{\n  \"version\": \"2.0\",\n  \"pipeline_stage\": \"validated\",\n  \"title\": \"Profound neuronal differences during Exercise-Induced Hypoalgesia between athletes and non-athletes revealed by functional near-infrared spectroscopy\",\n  \"description\": \"This functional near-infrared spectroscopy (fNIRS) dataset investigates neuronal mechanisms underlying exercise-induced hypoalgesia in endurance athletes versus non-athletes. Twenty-two athletes and twenty non-athletes performed high-intensity interval training (HIIT) while brain oxygenation was monitored across pain-processing regions including the prefrontal cortex, sensorimotor cortices, and posterior parietal cortex. The study reveals distinct neural activation patterns and pain reduction responses between groups, with athletes demonstrating greater oxyhemoglobin increases in the posterior parietal cortex during exercise and significant post-HIIT decreases in pain perception correlated with prefrontal cortex deactivation.\",\n  \"methods_description\": \"Participants underwent high-intensity interval training (HIIT) and pressure pain tests while brain oxygenation was monitored using functional near-infrared spectroscopy (fNIRS) covering the prefrontal cortex, sensorimotor cortices, and posterior parietal cortex. The study included 22 endurance athletes (mean age 33.3 ± 10.8 years) and 20 non-athletes (mean age 28.9 ± 9.0 years).\",\n  \"license\": \"CC0\",\n  \"dataset_type\": \"raw\",\n  \"authors\": {\n    \"Maria Geisler, Marco Herbsleb, Feliberto de la Cruz, Sabrina von Au, Andy Schumann, Ilona Croy, Karl-Jürgen Bär\": {}\n  },\n  \"keywords\": [\n    {\n      \"term\": \"fNIRS\"\n    },\n    {\n      \"term\": \"exercise-induced hypoalgesia\"\n    },\n    {\n      \"term\": \"pain processing\"\n    },\n    {\n      \"term\": \"prefrontal cortex\"\n    },\n    {\n      \"term\": \"high-intensity interval training\"\n    },\n    {\n      \"term\": \"oxyhemoglobin\"\n    },\n    {\n      \"term\": \"athletes\"\n    }\n  ],\n  \"related_identifiers\": [\n    {\n      \"identifier\": \"https://github.com/nemarDatasets/on006902\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"https://nemar.org/dataexplorer/detail?dataset_id=on006902\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"10.18112/openneuro.ds006902.v1.1.1\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsDerivedFrom\"\n    }\n  ],\n  \"resource_type_general\": \"Dataset\",\n  \"resource_type_specific\": \"fNIRS Dataset\",\n  \"modalities\": [\n    \"nirs\"\n  ],\n  \"sizes\": [\n    \"5.9 GB (43 files)\"\n  ],\n  \"formats\": [\n    \".json\",\n    \".md\",\n    \".snirf\",\n    \".tsv\",\n    \".yml\"\n  ],\n  \"source_hash\": \"09e596ae66db5224e8acde4863a19b120156ba6da067d3d9ff8c77eff6c97a49\"\n}","last_activity_at":"2026-06-18 23:07:58","source":"openneuro","source_id":"ds006902","subject_count":42,"modalities":"nirs","age_min":null,"age_max":null,"file_size":5914170752,"total_files":261,"tasks":"pain","metadata_columns_error":null,"staleness_warn_stage":null,"staleness_admin_notified_at":null,"authors":"Maria Geisler, Marco Herbsleb, Feliberto de la Cruz, Sabrina von Au, Andy Schumann, Ilona Croy, Karl-Jürgen Bär","license":"CC0","readme":"[![DOI](https://img.shields.io/badge/DOI-10.82901%2Fnemar.on006902-blue)](https://doi.org/10.82901/nemar.on006902)\n\nRegular physical activity is an important treatment constituent for chronic pain. To unravel the neuronal influence of exercise on pain, we investigated the neuronal changes during exercise-induced hypoalgesia in endurance athletes and controls. \nTwenty-two athletes (mean age: 33.3 ± 10.8 years) and twenty non-athletes (mean age: 28.9 ± 9.0 years) underwent High-Intensity Interval Training (HIIT) and pressure pain tests, while brain oxygenation was monitored using functional near-infrared spectroscopy to cover key regions of pain processing: the prefrontal cortex (PFC), sensory motor cortices, and posterior parietal cortex (PPC).\nDuring HIIT, both groups exhibited a steady increase in PFC oxyhemoglobin, with athletes showing a greater increase in the PPC area than non-athletes. As expected, athletes showed a significant reduction in pain perception after HIIT, whereas non-athletes did not. In line, athletes showed a significant decrease in oxyhemoglobin levels in all brain areas post-HIIT, while non-athletes only showed a decrease in sensory motor areas. Interestingly, in athletes, pain reduction correlated with the decrease in PFC oxyhemoglobin during painful stimulation, whereas no significant correlation was observed in non-athletes. \nThe pronounced HIIT-induced increase in oxyhemoglobin in athletes may elevate baseline neural activity to a level where additional activation is limited, potentially reducing the salience of pain-related signals. This athlete-specific response may result from endurance training adaptations, such as enhanced microvascularization and oxygen delivery, promoting greater neural efficiency during high-intensity exercise. These findings highlight HIIT's potential as a targeted pain management strategy for athletes and the need for tailored approaches in non-athletes.\n\ndataset: sub01-sub27 are athletes; sub29-sub53 are non-athletes","bids_version":"1.7.0","sessions_count":null,"publish_date":null,"embedding_dirty":0,"license_tier":"public","zarr_status":"ready","zarr_converted_at":"2026-09-06 02:52:13","zarr_store_count":0,"zarr_index_etag":"3e7812e3418f9eee0e87f7a21b2bb4f2","zarr_source_commit":"7e805525b7ebe0a5a32b62bca4c16cc39219fd97","archive_status":"ready","archive_size":3672852812,"archive_retry_count":0,"records_status":"ready","archive_skip_reason":null,"zarr_errors":0,"zarr_failure_count":0,"zarr_deterministic":0,"zarr_failed_at":null,"num_dataset_citations":0,"num_datapaper_citations":0,"n_channels":null,"electrode_system":null,"has_hed":0,"hed_version":null,"is_exemplar":0,"bytes_present":5913435180,"data_complete":1,"withdrawn_at":null,"withdrawn_reason":null,"archive_complete":null,"archive_absent_files":null,"archive_declared_files":null,"zarr_pool_breaks":0,"total_recording_duration":null,"recording_duration_min":null,"recording_duration_max":null,"recording_count":0,"recordings_unavailable":0,"recordings_measured":0,"channel_count_min":null,"channel_count_max":null,"sampling_frequency":null,"power_line_frequency":null,"eeg_reference":null,"placement_scheme":null,"sweep_stamps":"{\"enrichment_updated_at\":\"2026-06-18 23:14:51\",\"metadata_updated_at\":\"2026-06-18 23:14:55\",\"archive_checked_at\":\"2026-06-18 23:18:37\",\"zarr_checked_at\":null,\"records_checked_at\":\"2026-06-18 23:16:16\",\"citations_updated_at\":null,\"channel_montage_checked_at\":null,\"hed_checked_at\":\"2026-06-30 05:39:10\",\"data_checked_at\":\"2026-07-25 03:00:18\",\"availability_report_at\":\"2026-07-23 01:30:34\",\"signal_defaults_at\":\"2026-09-02 12:49:45\",\"recording_stats_at\":\"2026-09-06 03:01:08\"}","participants":42,"num_citations":0,"latest_version":"v1.0.0","zarr_verify_status":null,"zarr_verified_at":null,"owner_username":"nemarAdmin","owner_github":"nemarAdmin","file_size_formatted":"5.51 GB","zarr_data_failures":null,"zarr_index_url":"https://zarr.nemar.org/on006902/zarr/index.json","attestation_deposit_type":null,"attestation_key_status":null,"attestation_deidentified":null,"attestation_no_duplicate":null,"attestation_upstream_source":null,"attestation_accepted_at":null}}