{"dataset":{"id":"50316","dataset_id":"on006110","name":"PsiConnect","description":"PsiConnect is a large-scale multimodal neuroimaging study investigating context-dependent neural and subjective effects of psilocybin in 62 participants. The dataset combines functional, structural, and diffusion-weighted MRI with concurrent EEG acquired before and after psilocybin administration (19 mg), incorporating resting-state and naturalistic conditions (guided meditation, music listening, movie watching). Half the cohort completed an 8-week meditation training program, enabling investigation of interactions between meditation, psilocybin, and brain function. Comprehensive behavioral and self-report measures were collected acutely and longitudinally up to one year post-administration.","owner_user_id":15,"status":"active","github_repo":"nemarDatasets/on006110","concept_doi":"10.82901/nemar.on006110","latest_version_doi":"10.82901/nemar.on006110.v1.0.0","created_at":"2026-06-20 21:40:51","updated_at":"2026-07-22 22:46:01","zenodo_concept_id":null,"is_sandbox":0,"visibility":"public","ezid_status":"public","enrichment_json":"{\n  \"version\": \"2.0\",\n  \"pipeline_stage\": \"enriched\",\n  \"title\": \"PsiConnect\",\n  \"license\": \"CC0\",\n  \"dataset_type\": \"raw\",\n  \"authors\": {\n    \"Adeel Razi\": {\n      \"orcid\": \"0000-0002-0779-9439\"\n    }\n  },\n  \"related_identifiers\": [\n    {\n      \"identifier\": \"10.18112/openneuro.ds006110.v1.2.0\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsDerivedFrom\"\n    },\n    {\n      \"identifier\": \"https://github.com/nemarDatasets/on006110\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"https://nemar.org/dataset/on006110\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"10.1101/2025.04.11.643415\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"10.1101/2025.03.09.642197\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsDescribedBy\"\n    }\n  ],\n  \"funding_references\": [\n    {\n      \"funder_name\": \"CIFAR Azrieli Mind & Consciousness Program\"\n    },\n    {\n      \"funder_name\": \"USONA Institute Investigational Drug Supply Program\"\n    },\n    {\n      \"funder_name\": \"Australian Research Council\",\n      \"award_number\": \"DE170100128\"\n    },\n    {\n      \"funder_name\": \"Australian Research Council\",\n      \"award_number\": \"DP200100757\"\n    },\n    {\n      \"funder_name\": \"Australian National Health and Medical Research Council\",\n      \"award_number\": \"1194910\"\n    },\n    {\n      \"funder_name\": \"CIFAR\",\n      \"award_title\": \"Azrieli Global Scholar in the Brain, Mind & Consciousness Program\"\n    }\n  ],\n  \"resource_type_general\": \"Dataset\",\n  \"sizes\": [\n    \"1.0 TB (59933 files)\"\n  ],\n  \"formats\": [\n    \".2/fsaverage/label/Yeo_Brainmap_fsaverage_README\",\n    \".2/participant_id\",\n    \".2mm/README\",\n    \".3d\",\n    \".H\",\n    \".K\",\n    \".README\",\n    \".T1\",\n    \".T2\",\n    \".annot\",\n    \".area\",\n    \".avg\",\n    \".avg_curv\",\n    \".avg_sulc\",\n    \".avg_thickness\",\n    \".backup\",\n    \".bak\",\n    \".bib\",\n    \".bidsignore\",\n    \".cmd\",\n    \".crv\",\n    \".csv\",\n    \".ctab\",\n    \".curv\",\n    \".dat\",\n    \".dat~\",\n    \".defect_borders\",\n    \".defect_chull\",\n    \".defect_labels\",\n    \".done\",\n    \".env\",\n    \".flat\",\n    \".gii\",\n    \".gz\",\n    \".h5\",\n    \".html\",\n    \".inflated\",\n    \".inflated_avg\",\n    \".inflated_pre\",\n    \".jacobian_white\",\n    \".json\",\n    \".label\",\n    \".local-copy\",\n    \".log\",\n    \".lta\",\n    \".m3z\",\n    \".mat\",\n    \".md\",\n    \".mgh\",\n    \".mgz\",\n    \".mid\",\n    \".midthickness\",\n    \".mincost\",\n    \".nii\",\n    \".nofix\",\n    \".old\",\n    \".orig\",\n    \".orig_avg\",\n    \".param\",\n    \".pial\",\n    \".pial_avg\",\n    \".pial_semi_inflated\",\n    \".pointset\",\n    \".preaparc\",\n    \".premesh\",\n    \".reg\",\n    \".smoothwm\",\n    \".sphere\",\n    \".stats\",\n    \".sulc\",\n    \".sum\",\n    \".svg\",\n    \".tex\",\n    \".thickness\",\n    \".toml\",\n    \".touch\",\n    \".tsv\",\n    \".tsv#\",\n    \".txt\",\n    \".volume\",\n    \".white\",\n    \".white_avg\",\n    \".xfm\",\n    \".yaml\",\n    \".yml\"\n  ],\n  \"description\": \"PsiConnect is a large-scale multimodal neuroimaging study investigating context-dependent neural and subjective effects of psilocybin in 62 participants. The dataset combines functional, structural, and diffusion-weighted MRI with concurrent EEG acquired before and after psilocybin administration (19 mg), incorporating resting-state and naturalistic conditions (guided meditation, music listening, movie watching). Half the cohort completed an 8-week meditation training program, enabling investigation of interactions between meditation, psilocybin, and brain function. Comprehensive behavioral and self-report measures were collected acutely and longitudinally up to one year post-administration.\",\n  \"methods_description\": \"Multimodal neuroimaging acquisition including multi-echo fMRI (enhanced signal-to-noise ratio and reduced susceptibility artifacts), structural MRI, diffusion-weighted imaging, and concurrent EEG. Study design includes resting-state scans and three naturalistic conditions: guided meditation, music listening, and movie watching. Behavioral and self-report measures were collected at multiple timepoints including acute and longitudinal follow-ups to one year post-administration.\",\n  \"keywords\": [\n    {\n      \"term\": \"Psilocybin\",\n      \"subject_scheme\": \"MeSH\",\n      \"value_uri\": \"http://id.nlm.nih.gov/mesh/D011562\"\n    },\n    {\n      \"term\": \"fMRI\",\n      \"subject_scheme\": \"MeSH\",\n      \"value_uri\": \"http://id.nlm.nih.gov/mesh/D000080788\"\n    },\n    {\n      \"term\": \"EEG\",\n      \"subject_scheme\": \"MeSH\",\n      \"value_uri\": \"http://id.nlm.nih.gov/mesh/D004569\"\n    },\n    {\n      \"term\": \"Brain Mapping\",\n      \"subject_scheme\": \"MeSH\",\n      \"value_uri\": \"http://id.nlm.nih.gov/mesh/D001931\"\n    },\n    {\n      \"term\": \"multimodal neuroimaging\"\n    },\n    {\n      \"term\": \"meditation\"\n    },\n    {\n      \"term\": \"psychedelics\"\n    },\n    {\n      \"term\": \"resting-state\"\n    },\n    {\n      \"term\": \"diffusion-weighted imaging\"\n    },\n    {\n      \"term\": \"structural MRI\"\n    },\n    {\n      \"term\": \"naturalistic viewing\"\n    },\n    {\n      \"term\": \"consciousness\"\n    },\n    {\n      \"term\": \"altered states\"\n    }\n  ],\n  \"source_hash\": \"4024814c93111b05e6146160e1fd64cbba57313a373f144c6bb320e92a906069\"\n}","last_activity_at":"2026-06-20 21:40:51","source":"openneuro","source_id":"ds006110","subject_count":65,"modalities":"anat,dwi,eeg,fmap,func","age_min":null,"age_max":null,"file_size":1004663010141,"total_files":79510,"tasks":"meditation,movie,music,rest,series","metadata_columns_error":null,"staleness_warn_stage":null,"staleness_admin_notified_at":null,"authors":"Adeel Razi","license":"CC0","readme":"[![DOI](https://img.shields.io/badge/DOI-10.82901%2Fnemar.on006110-blue)](https://doi.org/10.82901/nemar.on006110)\n\nPsiConnect is a large-scale neuroimaging study designed to investigate context-dependent neural and subjective effects of psilocybin using multimodal neuroimaging. It combines functional, structural, and diffusion-weighted MRI with EEG to examine brain activity in 62 participants before and after a 19 mg dose of psilocybin. The design includes resting-state scans and three naturalistic conditions: guided meditation, music listening, and movie watching. Half of the cohort underwent an 8-week meditation training program, enabling exploration of interactions among meditation, psilocybin, and brain function. fMRI data was obtained through multi-echo fMRI, enhancing signal-to-noise ratio and reducing susceptibility artifacts to improve reliability. A comprehensive battery of behavioural and self-report measures captured acute and longitudinal cognitive and subjective effects, with follow-ups to one year post-administration. The large sample, multimodal imaging, contextual diversity, and behavioural follow-ups enable study of psilocybin-induced brain and behaviour changes with unprecedented comprehensiveness and reliability. Data is curated according to open science principles to ensure accessibility and compatibility with established neuroimaging pipelines, making PsiConnect a valuable, reusable resource for cognitive and computational neuroscience.\n\nPlease cite both:\n\n- Novelli, L. et al. (2025). PsiConnect: A Multimodal Neuroimaging Study of Psilocybin-Induced Changes in Brain and Behaviour. https://doi.org/10.1101/2025.04.11.643415\n\n- Stoliker, D. et al. (2025). Psychedelics Align Brain Activity with Context. 2025. https://doi.org/10.1101/2025.03.09.642197\n","bids_version":"1.7.0","sessions_count":2,"publish_date":null,"embedding_dirty":0,"license_tier":"public","zarr_status":"ready","zarr_converted_at":"2026-09-06 18:01:31","zarr_store_count":124,"zarr_index_etag":"566311e198309dbe501174311eabfd13","zarr_source_commit":"ca842744348695248eaa7e49030777c5f3bae647","archive_status":null,"archive_size":null,"archive_retry_count":0,"records_status":"ready","archive_skip_reason":null,"zarr_errors":0,"zarr_failure_count":0,"zarr_deterministic":0,"zarr_failed_at":null,"num_dataset_citations":0,"num_datapaper_citations":0,"n_channels":64,"electrode_system":"10-10","has_hed":0,"hed_version":null,"is_exemplar":0,"bytes_present":1001617174483,"data_complete":0,"withdrawn_at":null,"withdrawn_reason":null,"archive_complete":null,"archive_absent_files":null,"archive_declared_files":null,"zarr_pool_breaks":0,"total_recording_duration":166610.35999999996,"recording_duration_min":1263.2,"recording_duration_max":1680.32,"recording_count":124,"recordings_unavailable":0,"recordings_measured":124,"channel_count_min":66,"channel_count_max":67,"sampling_frequency":500,"power_line_frequency":50,"eeg_reference":"single electrode placed on FCz","placement_scheme":"10 percent system","sweep_stamps":"{\"enrichment_updated_at\":\"2026-07-22 22:45:24\",\"metadata_updated_at\":\"2026-07-22 22:46:00\",\"archive_checked_at\":null,\"zarr_checked_at\":null,\"records_checked_at\":\"2026-06-21 01:09:15\",\"citations_updated_at\":\"2026-09-08 03:00:54\",\"channel_montage_checked_at\":\"2026-06-28 23:53:47\",\"hed_checked_at\":\"2026-06-30 05:31:00\",\"data_checked_at\":\"2026-07-22 22:48:22\",\"availability_report_at\":\"2026-07-23 01:03:05\",\"signal_defaults_at\":\"2026-09-02 12:43:31\",\"recording_stats_at\":\"2026-09-07 03:01:13\"}","participants":65,"num_citations":0,"latest_version":"v1.0.0","zarr_verify_status":null,"zarr_verified_at":null,"owner_username":"nemarAdmin","owner_github":"nemarAdmin","file_size_formatted":"936 GB","zarr_data_failures":null,"zarr_index_url":"https://zarr.nemar.org/on006110/zarr/index.json","attestation_deposit_type":null,"attestation_key_status":null,"attestation_deidentified":null,"attestation_no_duplicate":null,"attestation_upstream_source":null,"attestation_accepted_at":null}}