{"dataset":{"id":"60162","dataset_id":"on005169","name":"Dataset of intracranial EEG during cortical stimulation evoking visual effects","description":"This dataset comprises intracranial EEG (iEEG) recordings from 22 patients undergoing stereo-EEG presurgical evaluation for drug-resistant epilepsy, capturing responses to 115 high-frequency cortical stimulations that evoked visual hallucinations. Each recording includes 21 seconds of iEEG data surrounding each stimulation event, with detailed annotations of stimulation parameters and 14 categories of evoked clinical visual phenomena. The dataset supports investigation of brain networks underlying stimulation-evoked visual symptoms and enables construction of symptom-related activation and connectivity maps.","owner_user_id":15,"status":"active","github_repo":"nemarDatasets/on005169","concept_doi":"10.82901/nemar.on005169","latest_version_doi":"10.82901/nemar.on005169.v1.0.0","created_at":"2026-06-26 12:01:45","updated_at":"2026-08-19 02:00:26","zenodo_concept_id":null,"is_sandbox":0,"visibility":"public","ezid_status":"public","enrichment_json":"{\n  \"version\": \"2.0\",\n  \"pipeline_stage\": \"validated\",\n  \"title\": \"Dataset of intracranial EEG during cortical stimulation evoking visual effects\",\n  \"description\": \"This dataset comprises intracranial EEG (iEEG) recordings from 22 patients undergoing stereo-EEG presurgical evaluation for drug-resistant epilepsy, capturing responses to 115 high-frequency cortical stimulations that evoked visual hallucinations. Each recording includes 21 seconds of iEEG data surrounding each stimulation event, with detailed annotations of stimulation parameters and 14 categories of evoked clinical visual phenomena. The dataset supports investigation of brain networks underlying stimulation-evoked visual symptoms and enables construction of symptom-related activation and connectivity maps.\",\n  \"methods_description\": \"High-frequency bipolar intracranial stimulations were delivered using alternating polarity biphasic pulses of 1 ms duration at 43.2 Hz or 50 Hz, with current intensities between 0.25 and 3 mA, for up to 5 seconds. The alternating polarity protocol was used to disambiguate neuronal responses time-locked to stimulation from artefactual components. Recordings span 8 seconds before stimulation onset, the stimulation period (up to 5 s), and 8 seconds after stimulation offset. Stimulation contact pairs, current intensity, and evoked clinical effects were documented in accompanying events files.\",\n  \"license\": \"CC0\",\n  \"dataset_type\": \"raw\",\n  \"authors\": {\n    \"Andrei Barborica\": {\n      \"orcid\": \"0000-0001-6783-3769\",\n      \"affiliations\": [\n        {\n          \"name\": \"Physics Department University of Bucharest  Bucharest Romania\"\n        },\n        {\n          \"name\": \"FHC Inc.  Bowdoin Maine USA\"\n        }\n      ]\n    },\n    \"Felicia Mihai\": {\n      \"orcid\": \"0000-0001-7324-5525\",\n      \"affiliations\": [\n        {\n          \"name\": \"Physics Department University of Bucharest  Bucharest Romania\"\n        }\n      ]\n    },\n    \"Laurentiu Tofan\": {},\n    \"Irina Oane\": {\n      \"orcid\": \"0000-0002-3796-0676\",\n      \"affiliations\": [\n        {\n          \"name\": \"Epilepsy Monitoring Unit, Neurology Department Emergency University Hospital Bucharest  Bucharest Romania\"\n        }\n      ]\n    },\n    \"Ioana Mindruta\": {\n      \"orcid\": \"0000-0001-9329-5132\",\n      \"affiliations\": [\n        {\n          \"name\": \"Epilepsy Monitoring Unit, Neurology Department Emergency University Hospital Bucharest  Bucharest Romania\"\n        },\n        {\n          \"name\": \"Neurology Department, Faculty of Medicine Carol Davila University of Medicine and Pharmacy Bucharest  Bucharest Romania\"\n        }\n      ]\n    }\n  },\n  \"keywords\": [\n    {\n      \"term\": \"Electroencephalography\",\n      \"subject_scheme\": \"MeSH\",\n      \"value_uri\": \"http://id.nlm.nih.gov/mesh/D004569\"\n    },\n    {\n      \"term\": \"intracranial EEG\"\n    },\n    {\n      \"term\": \"cortical stimulation\"\n    },\n    {\n      \"term\": \"visual hallucinations\"\n    },\n    {\n      \"term\": \"Epilepsy\",\n      \"subject_scheme\": \"MeSH\",\n      \"value_uri\": \"http://id.nlm.nih.gov/mesh/D004827\"\n    },\n    {\n      \"term\": \"stereo-EEG\"\n    },\n    {\n      \"term\": \"presurgical evaluation\"\n    },\n    {\n      \"term\": \"brain connectivity\"\n    },\n    {\n      \"term\": \"stimulation mapping\"\n    },\n    {\n      \"term\": \"high-frequency stimulation\"\n    }\n  ],\n  \"related_identifiers\": [\n    {\n      \"identifier\": \"https://github.com/nemarDatasets/on005169\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"10.1002/hbm.25749\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"10.18112/openneuro.ds005169.v1.0.0\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsDerivedFrom\"\n    },\n    {\n      \"identifier\": \"https://nemar.org/dataset/on005169\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    }\n  ],\n  \"funding_references\": [\n    {\n      \"funder_name\": \"Romanian UEFISCDI\",\n      \"award_number\": \"PN-III-P4-ID-PCE-2020-0935\"\n    }\n  ],\n  \"resource_type_general\": \"Dataset\",\n  \"resource_type_specific\": \"Structural MRI Dataset\",\n  \"modalities\": [\n    \"anat\",\n    \"ieeg\"\n  ],\n  \"sizes\": [\n    \"4.3 GB (355 files)\"\n  ],\n  \"formats\": [\n    \".eeg\",\n    \".json\",\n    \".md\",\n    \".nii\",\n    \".tsv\",\n    \".vhdr\",\n    \".vmrk\",\n    \".yml\"\n  ],\n  \"source_hash\": \"0fb3263d468f48ddad6a32324b9244c9cc05be59788f3dcd119e5b59f55bdaa5\"\n}","last_activity_at":"2026-06-26 12:01:45","source":"openneuro","source_id":"ds005169","subject_count":20,"modalities":"anat,ieeg","age_min":18,"age_max":47,"file_size":4322726251,"total_files":1169,"tasks":"dcs","metadata_columns_error":null,"staleness_warn_stage":null,"staleness_admin_notified_at":null,"authors":"Andrei Barborica, Felicia Mihai, Laurentiu Tofan, Irina Oane, Ioana Mindruta","license":"CC0","readme":"[![DOI](https://img.shields.io/badge/DOI-10.82901%2Fnemar.on005169-blue)](https://doi.org/10.82901/nemar.on005169)\n\nIn this dataset we included iEEG recordings of responses to 115 intracranial high frequency stimulations evoking \nvisual hallucinations, in 22 patients undergoing stereo-EEG presurgical evaluation for drug-resistant epilepsy.\n\nThe dataset contains 21 seconds of iEEG data around each stimulation, 8 seconds before the start of the stimulation, \nup to 5 seconds of intracranial stimulation and 8 seconds after the end of the stimulation.\n\nWe have used high-frequency bipolar stimulations of different areas of the brain, using alternating polarity \nbiphasic pulses having a duration of 1 ms, at 43.2 Hz or 50 Hz, current intensity between 0.25 to 3 mA, for up to 5 s. \nAlternating polarity protocol allows disambiguating neuronal responses time-locked to the stimulation pulses \nfrom the artefactual components, according to Barborica et al., 2022 (doi: 10.1002/hbm.25749). It is therefore \npossible to identify the brain networks underlying the clinical effects, and to create symptom-related \nactivation/connectivity maps.\n\nThe contact pair on which stimulation is applied, the current intensity level and evoked effect are specified \nin the events tsv. The responses are classified in 14 clinical categories: elementary (unstructured \nflashes of light), plus hallucination (presence of light in different forms or colors overlaying the background vision), \nminus hallucination (negative elementary phenomena described as scotoma, quadrantanopia, hemianopia or amaurosis), \nstatic, dynamic, continuous hallucination, intermittent hallucination, peripheric, central, \nwhole visual field, color, non-color, combined visual symptoms, multimodal hallucinations.\n\nNot all patients in which stimulations evoked visual hallucinations met the inclusion criteria for network analysis \nthat requires running the freesurfer pipeline, for instance patients having prior resections, therefore there are subjects\nthat do not contain ieeg data. However, they were kept in order to match the number of patients in the companion manuscript.\n\nContact: andrei.barborica@fizica.unibuc.ro","bids_version":"1.9.0","sessions_count":16,"publish_date":null,"embedding_dirty":0,"license_tier":"public","zarr_status":"ready","zarr_converted_at":"2026-08-19 10:33:58","zarr_store_count":112,"zarr_index_etag":"d114020388b9abfeff7c2fabf01dd3ad","zarr_source_commit":"0bb00199a4e8bc02fde6a32305dd89511ba47dc9","archive_status":"ready","archive_size":2434453789,"archive_retry_count":0,"records_status":"ready","archive_skip_reason":null,"zarr_errors":0,"zarr_failure_count":0,"zarr_deterministic":0,"zarr_failed_at":null,"num_dataset_citations":0,"num_datapaper_citations":10,"n_channels":null,"electrode_system":null,"has_hed":0,"hed_version":null,"is_exemplar":0,"bytes_present":4268176035,"data_complete":1,"withdrawn_at":null,"withdrawn_reason":null,"archive_complete":null,"archive_absent_files":null,"archive_declared_files":null,"zarr_pool_breaks":null,"total_recording_duration":2352,"recording_duration_min":21,"recording_duration_max":21,"recording_count":112,"recordings_unavailable":0,"recordings_measured":112,"channel_count_min":29,"channel_count_max":193,"sampling_frequency":null,"power_line_frequency":null,"eeg_reference":null,"placement_scheme":null,"sweep_stamps":"{\"enrichment_updated_at\":\"2026-08-19 02:00:08\",\"metadata_updated_at\":\"2026-08-19 02:00:25\",\"archive_checked_at\":\"2026-06-26 12:13:01\",\"zarr_checked_at\":null,\"records_checked_at\":\"2026-06-26 12:11:10\",\"citations_updated_at\":\"2026-09-08 03:00:49\",\"channel_montage_checked_at\":\"2026-06-28 23:38:45\",\"hed_checked_at\":\"2026-06-30 05:12:25\",\"data_checked_at\":\"2026-08-19 03:00:06\",\"availability_report_at\":\"2026-07-23 01:22:55\",\"recording_stats_at\":\"2026-09-02 11:33:10\",\"signal_defaults_at\":\"2026-09-02 12:25:32\"}","participants":20,"num_citations":10,"latest_version":"v1.0.0","zarr_verify_status":null,"zarr_verified_at":null,"owner_username":"nemarAdmin","owner_github":"nemarAdmin","file_size_formatted":"4.03 GB","zarr_data_failures":null,"zarr_index_url":"https://zarr.nemar.org/on005169/zarr/index.json","attestation_deposit_type":null,"attestation_key_status":null,"attestation_deidentified":null,"attestation_no_duplicate":null,"attestation_upstream_source":null,"attestation_accepted_at":null}}