{"dataset":{"id":"57130","dataset_id":"on004457","name":"Electrical stimulation of temporal and limbic circuitry produces distinct responses in human ventral temporal cortex","description":"This dataset comprises intracranial EEG recordings from five patients undergoing single-pulse electrical stimulation of temporal and limbic circuitry at Mayo Clinic. The study investigates Basis Profile Curve identification and distinct neural responses evoked in human ventral temporal cortex through direct brain stimulation, providing insights into functional connectivity and processing speed within the human connectome.","owner_user_id":15,"status":"active","github_repo":"nemarDatasets/on004457","concept_doi":"10.82901/nemar.on004457","latest_version_doi":"10.82901/nemar.on004457.v1.0.0","created_at":"2026-06-24 09:31:42","updated_at":"2026-07-10 22:31:45","zenodo_concept_id":null,"is_sandbox":0,"visibility":"public","ezid_status":"public","enrichment_json":"{\n  \"version\": \"2.0\",\n  \"pipeline_stage\": \"validated\",\n  \"title\": \"Electrical stimulation of temporal and limbic circuitry produces distinct responses in human ventral temporal cortex\",\n  \"description\": \"This dataset comprises intracranial EEG recordings from five patients undergoing single-pulse electrical stimulation of temporal and limbic circuitry at Mayo Clinic. The study investigates Basis Profile Curve identification and distinct neural responses evoked in human ventral temporal cortex through direct brain stimulation, providing insights into functional connectivity and processing speed within the human connectome.\",\n  \"methods_description\": \"Intracranial EEG recordings were collected during single-pulse electrical stimulation delivered at approximately 0.2 Hz frequency. Stimulation parameters included 200-microsecond duration, biphasic waveform, and 6 mA amplitude. Patients were at rest during the recording sessions.\",\n  \"license\": \"CC0\",\n  \"dataset_type\": \"raw\",\n  \"authors\": {\n    \"Harvey Huang\": {\n      \"orcid\": \"0000-0002-0540-697X\"\n    },\n    \"Nicholas M Gregg\": {\n      \"orcid\": \"0000-0002-6151-043X\"\n    },\n    \"Gabriela Ojeda Valencia\": {},\n    \"Benjamin H Brinkmann\": {\n      \"orcid\": \"0000-0002-2392-8608\"\n    },\n    \"Brian N Lundstrom\": {\n      \"orcid\": \"0000-0002-5310-5549\"\n    },\n    \"Gregory A Worrell\": {\n      \"orcid\": \"0000-0003-2916-0553\"\n    },\n    \"Kai J Miller\": {\n      \"orcid\": \"0000-0002-6687-6422\"\n    },\n    \"Dora Hermes\": {\n      \"orcid\": \"0000-0002-8683-8909\"\n    }\n  },\n  \"keywords\": [\n    {\n      \"term\": \"intracranial EEG\"\n    },\n    {\n      \"term\": \"electrical stimulation\"\n    },\n    {\n      \"term\": \"ventral temporal cortex\"\n    },\n    {\n      \"term\": \"temporal lobe\"\n    },\n    {\n      \"term\": \"limbic system\"\n    },\n    {\n      \"term\": \"Evoked Potentials\",\n      \"subject_scheme\": \"MeSH\",\n      \"value_uri\": \"http://id.nlm.nih.gov/mesh/D005071\"\n    },\n    {\n      \"term\": \"connectome\"\n    },\n    {\n      \"term\": \"Basis Profile Curve\"\n    }\n  ],\n  \"related_identifiers\": [\n    {\n      \"identifier\": \"10.1101/2022.07.06.498994\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"References\"\n    },\n    {\n      \"identifier\": \"https://github.com/nemarDatasets/on004457\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"https://nemar.org/dataexplorer/detail?dataset_id=on004457\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"10.18112/openneuro.ds004457.v1.0.1\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsDerivedFrom\"\n    }\n  ],\n  \"funding_references\": [\n    {\n      \"funder_name\": \"R01 MH122258 CRCNS: Processing speed in the human connectome across the lifespan\"\n    },\n    {\n      \"funder_name\": \"T32 GM065841: Medical Scientist Training Program at Mayo Clinic\"\n    },\n    {\n      \"funder_name\": \"National Institute of Mental Health\",\n      \"award_number\": \"R01MH122258\",\n      \"award_title\": \"CRCNS: Processing speed in the human connectome across the lifespan\"\n    },\n    {\n      \"funder_name\": \"National Institute of General Medical Sciences\",\n      \"award_number\": \"T32GM065841\",\n      \"award_title\": \"Medical Scientist Training Program at Mayo Clinic\"\n    }\n  ],\n  \"resource_type_specific\": \"iEEG Dataset\",\n  \"modalities\": [\n    \"ieeg\"\n  ],\n  \"sizes\": [\n    \"12.3 GB (2764 files)\"\n  ],\n  \"formats\": [\n    \".annot\",\n    \".gii\",\n    \".gz\",\n    \".json\",\n    \".mat\",\n    \".md\",\n    \".mgz\",\n    \".nii\",\n    \".sulc\",\n    \".tdat\",\n    \".tidx\",\n    \".tif\",\n    \".tmet\",\n    \".tsv\",\n    \".txt\",\n    \".yml\"\n  ],\n  \"source_hash\": \"ecf917300d6e460a12de7cf7a766e4e279827f5d3df1ab4ac59d330e6f3f711e\"\n}","last_activity_at":"2026-06-24 09:31:42","source":"openneuro","source_id":"ds004457","subject_count":5,"modalities":"ieeg","age_min":13,"age_max":46,"file_size":12258420918,"total_files":2803,"tasks":"ccep","metadata_columns_error":null,"staleness_warn_stage":null,"staleness_admin_notified_at":null,"authors":"Harvey Huang, Nicholas M Gregg, Gabriela Ojeda Valencia, Benjamin H Brinkmann, Brian N Lundstrom, Gregory A Worrell, Kai J Miller, Dora Hermes","license":"CC0","readme":"[![DOI](https://img.shields.io/badge/DOI-10.82901%2Fnemar.on004457-blue)](https://doi.org/10.82901/nemar.on004457)\n\n# Basis Profile Curve identification in the human ventral temporal cortex\n\nThis dataset contains intracranial EEG recordings from five patients during single pulse electrical stimulation as described in:\n \n* H Huang, NM Gregg, G Ojeda Valencia, BH Brinkmann, BN Lundstrom, GA Worrell, KJ Miller, and D Hermes (2022) Electrical stimulation of temporal and limbic circuitry produces distinct responses in human ventral temporal cortex. (Under Review)\n\nPlease cite this work when using the data. These data were recorded at the Mayo Clinic in Rochester, MN, as part of the NIH Brain Initiative supported project R01 MH122258 \"CRCNS: Processing speed in the human connectome across the lifespan\". Research reported in this publication was supported by the National Institute Of Mental Health of the National Institutes of Health under Award Number R01MH122258 and by the National Institute of General Medical Sciences of the National Institutes of Health under Award Number T32GM065841. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The data was collected by Harvey Huang, Dora Hermes, Nick Gregg, Brian Lundstrom, Cindy Nelson, Gregg Worrell and Kai J. Miller. The BIDS formatting was performed by Harvey Huang, Dora Hermes and Gabriela Ojeda Valencia. \n\nData can be analyzed using the Matlab code at: \n* https://github.com/hharveygit/VTCBPC_JNS_Manu\n\n## Format\nData are formatted according to BIDS version 1.9.9\n\n## Single pulse stimulation\nThe patient were resting in the hospital bed, while single pulse stimulation was performed with a frequency of ~0.2 Hz. The stimulation had a duration of 200 microseconds, was biphasic and had an amplitude of 6mA.\n\n## Contact\nPlease contact Dora Hermes (hermes.dora@mayo.edu) for questions. \n","bids_version":"v 1.9.9","sessions_count":1,"publish_date":null,"embedding_dirty":0,"license_tier":"public","zarr_status":"ready","zarr_converted_at":"2026-08-06 20:32:30","zarr_store_count":0,"zarr_index_etag":"7d46073b32d396de6cfce2a06d87bce0","zarr_source_commit":"2839852b9dac362df41feebf3ce973eaa7ecd1ac","archive_status":"ready","archive_size":11463501752,"archive_retry_count":0,"records_status":"ready","archive_skip_reason":null,"zarr_errors":0,"zarr_failure_count":0,"zarr_deterministic":0,"zarr_failed_at":null,"num_dataset_citations":1,"num_datapaper_citations":14,"n_channels":null,"electrode_system":null,"has_hed":0,"hed_version":null,"is_exemplar":0,"bytes_present":12257950917,"data_complete":1,"withdrawn_at":null,"withdrawn_reason":null,"archive_complete":null,"archive_absent_files":null,"archive_declared_files":null,"zarr_pool_breaks":null,"total_recording_duration":null,"recording_duration_min":null,"recording_duration_max":null,"recording_count":0,"recordings_unavailable":0,"recordings_measured":0,"channel_count_min":null,"channel_count_max":null,"sampling_frequency":null,"power_line_frequency":null,"eeg_reference":null,"placement_scheme":null,"sweep_stamps":"{\"enrichment_updated_at\":\"2026-06-24 09:43:55\",\"metadata_updated_at\":\"2026-06-24 09:44:06\",\"archive_checked_at\":\"2026-06-24 09:57:30\",\"zarr_checked_at\":null,\"records_checked_at\":\"2026-06-24 09:44:40\",\"citations_updated_at\":\"2026-09-08 03:00:49\",\"channel_montage_checked_at\":\"2026-06-28 23:25:36\",\"hed_checked_at\":\"2026-06-30 04:59:12\",\"data_checked_at\":\"2026-08-10 03:00:44\",\"availability_report_at\":\"2026-07-23 01:18:58\",\"recording_stats_at\":\"2026-09-02 11:32:45\",\"signal_defaults_at\":\"2026-09-02 12:13:09\"}","participants":5,"num_citations":15,"latest_version":"v1.0.0","zarr_verify_status":null,"zarr_verified_at":null,"owner_username":"nemarAdmin","owner_github":"nemarAdmin","file_size_formatted":"11.42 GB","zarr_data_failures":null,"zarr_index_url":"https://zarr.nemar.org/on004457/zarr/index.json","attestation_deposit_type":null,"attestation_key_status":null,"attestation_deidentified":null,"attestation_no_duplicate":null,"attestation_upstream_source":null,"attestation_accepted_at":null}}