{"dataset":{"id":"54525","dataset_id":"on004024","name":"TMS-EEG-MRI-fMRI-DWI data on paired associative stimulation and connectivity (Shirley Ryan AbilityLab, Chicago, IL)","description":"This dataset comprises multimodal neuroimaging data from a bifocal transcranial magnetic stimulation (TMS) study investigating cortico-cortical paired associative stimulation (ccPAS) and its effects on interhemispheric motor cortex connectivity. Participants underwent TMS-EEG recordings targeting bilateral primary motor cortex with varying interstimulus intervals (4, 9, and 14 ms), combined with structural and functional MRI acquisitions. The dataset includes 64-channel EEG recordings, resting-state fMRI, high-angular-resolution diffusion imaging, and anatomical MRI to characterize spike-timing-dependent plasticity mechanisms in human motor networks.","owner_user_id":15,"status":"active","github_repo":"nemarDatasets/on004024","concept_doi":"10.82901/nemar.on004024","latest_version_doi":"10.82901/nemar.on004024.v1.0.0","created_at":"2026-06-23 03:01:49","updated_at":"2026-07-10 22:23:57","zenodo_concept_id":null,"is_sandbox":0,"visibility":"public","ezid_status":"public","enrichment_json":"{\n  \"version\": \"2.0\",\n  \"pipeline_stage\": \"validated\",\n  \"title\": \"TMS-EEG-MRI-fMRI-DWI data on paired associative stimulation and connectivity (Shirley Ryan AbilityLab, Chicago, IL)\",\n  \"description\": \"This dataset comprises multimodal neuroimaging data from a bifocal transcranial magnetic stimulation (TMS) study investigating cortico-cortical paired associative stimulation (ccPAS) and its effects on interhemispheric motor cortex connectivity. Participants underwent TMS-EEG recordings targeting bilateral primary motor cortex with varying interstimulus intervals (4, 9, and 14 ms), combined with structural and functional MRI acquisitions. The dataset includes 64-channel EEG recordings, resting-state fMRI, high-angular-resolution diffusion imaging, and anatomical MRI to characterize spike-timing-dependent plasticity mechanisms in human motor networks.\",\n  \"methods_description\": \"EEG was recorded from 64 channels in DC mode (reference: right mastoid) with electrode locations digitized for source analysis. Bifocal MRI-navigated TMS targeted the first dorsal interossei representation in bilateral primary motor cortex. Paired associative stimulation consisted of left M1 stimulation at t=0 ms followed by right M1 stimulation at asynchronies of 4, 9, or 14 ms across three sessions. Single-pulse TMS at 100% or 110% resting motor threshold was delivered before, 10 minutes after, and 60 minutes after ccPAS. Resting-state EEG (eyes open, fixation) was collected at baseline, pre-ccPAS, and post-ccPAS timepoints. MRI protocols included T1-weighted structural imaging, resting-state fMRI, and HARDI diffusion imaging (SMS 271 directions) in subsets of participants.\",\n  \"license\": \"CC0\",\n  \"dataset_type\": \"raw\",\n  \"authors\": {\n    \"Julio Cesar Hernandez Pavon\": {},\n    \"Nils Schneider Garces\": {},\n    \"John Patrick Begnoche\": {},\n    \"Lee Miller\": {},\n    \"Tommi Raij\": {}\n  },\n  \"keywords\": [\n    {\n      \"term\": \"Transcranial Magnetic Stimulation\",\n      \"subject_scheme\": \"MeSH\",\n      \"value_uri\": \"http://id.nlm.nih.gov/mesh/D050781\"\n    },\n    {\n      \"term\": \"EEG\"\n    },\n    {\n      \"term\": \"Motor Cortex\",\n      \"subject_scheme\": \"MeSH\",\n      \"value_uri\": \"http://id.nlm.nih.gov/mesh/D009044\"\n    },\n    {\n      \"term\": \"paired associative stimulation\"\n    },\n    {\n      \"term\": \"functional connectivity\"\n    },\n    {\n      \"term\": \"diffusion weighted imaging\"\n    },\n    {\n      \"term\": \"neuroplasticity\"\n    }\n  ],\n  \"related_identifiers\": [\n    {\n      \"identifier\": \"https://github.com/nemarDatasets/on004024\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"https://nemar.org/dataexplorer/detail?dataset_id=on004024\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"10.21105/joss.01896\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsReferencedBy\"\n    },\n    {\n      \"identifier\": \"10.1038/s41597-019-0104-8\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsReferencedBy\"\n    },\n    {\n      \"identifier\": \"10.18112/openneuro.ds004024.v1.0.1\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsDerivedFrom\"\n    }\n  ],\n  \"funding_references\": [\n    {\n      \"funder_name\": \"Dr. Ralph and Marian Falk Medical Research Trust\"\n    }\n  ],\n  \"resource_type_general\": \"Dataset\",\n  \"resource_type_specific\": \"EEG Dataset\",\n  \"modalities\": [\n    \"eeg\",\n    \"anat\",\n    \"func\",\n    \"dwi\"\n  ],\n  \"sizes\": [\n    \"1.1 TB (1522 files)\"\n  ],\n  \"formats\": [\n    \".bval\",\n    \".bvec\",\n    \".eeg\",\n    \".gz\",\n    \".json\",\n    \".md\",\n    \".tsv\",\n    \".vhdr\",\n    \".vmrk\",\n    \".yml\"\n  ],\n  \"source_hash\": \"7393e4b5bce6bba868b97484959dd9dabcd28e0c62783c389d0b42390d28ea66\"\n}","last_activity_at":"2026-06-23 03:01:49","source":"openneuro","source_id":"ds004024","subject_count":13,"modalities":"anat,dwi,eeg,func","age_min":null,"age_max":null,"file_size":1096522009971,"total_files":3145,"tasks":"ccPAS,rest,spTMS","metadata_columns_error":null,"staleness_warn_stage":null,"staleness_admin_notified_at":null,"authors":"Julio Cesar Hernandez Pavon, Nils Schneider Garces, John Patrick Begnoche, Lee Miller, Tommi Raij","license":"CC0","readme":"[![DOI](https://img.shields.io/badge/DOI-10.82901%2Fnemar.on004024-blue)](https://doi.org/10.82901/nemar.on004024)\n\nReferences\n----------\nAppelhoff, S., Sanderson, M., Brooks, T., Vliet, M., Quentin, R., Holdgraf, C., Chaumon, M., Mikulan, E., Tavabi, K., Höchenberger, R., Welke, D., Brunner, C., Rockhill, A., Larson, E., Gramfort, A. and Jas, M. (2019). MNE-BIDS: Organizing electrophysiological data into the BIDS format and facilitating their analysis. Journal of Open Source Software 4: (1896). https://doi.org/10.21105/joss.01896\n\nPernet, C. R., Appelhoff, S., Gorgolewski, K. J., Flandin, G., Phillips, C., Delorme, A., Oostenveld, R. (2019). EEG-BIDS, an extension to the brain imaging data structure for electroencephalography. Scientific Data, 6, 103. https://doi.org/10.1038/s41597-019-0104-8\n\n","bids_version":"1.6.0","sessions_count":4,"publish_date":null,"embedding_dirty":0,"license_tier":"public","zarr_status":"ready","zarr_converted_at":"2026-08-05 06:19:01","zarr_store_count":497,"zarr_index_etag":"fa4af3deaed5a27a029c6c414cedec08","zarr_source_commit":"e4637b9a80f680bb375217f467d6df50c55f5b33","archive_status":null,"archive_size":null,"archive_retry_count":0,"records_status":"ready","archive_skip_reason":"dataset 1021.2 GB exceeds 100.0 GB archive limit; use direct download","zarr_errors":0,"zarr_failure_count":0,"zarr_deterministic":0,"zarr_failed_at":null,"num_dataset_citations":7,"num_datapaper_citations":0,"n_channels":64,"electrode_system":"10-10","has_hed":0,"hed_version":null,"is_exemplar":0,"bytes_present":1096516846551,"data_complete":1,"withdrawn_at":null,"withdrawn_reason":null,"archive_complete":null,"archive_absent_files":null,"archive_declared_files":null,"zarr_pool_breaks":null,"total_recording_duration":196201.45200000002,"recording_duration_min":58.78,"recording_duration_max":1153.776,"recording_count":497,"recordings_unavailable":0,"recordings_measured":497,"channel_count_min":69,"channel_count_max":69,"sampling_frequency":20000,"power_line_frequency":60,"eeg_reference":null,"placement_scheme":"based on the extended 10/20 system","sweep_stamps":"{\"enrichment_updated_at\":\"2026-06-23 03:36:28\",\"metadata_updated_at\":\"2026-06-23 03:36:37\",\"archive_checked_at\":\"2026-06-23 03:36:54\",\"zarr_checked_at\":null,\"records_checked_at\":\"2026-06-23 03:37:33\",\"citations_updated_at\":\"2026-09-08 03:00:50\",\"channel_montage_checked_at\":\"2026-06-28 23:18:35\",\"hed_checked_at\":\"2026-06-30 04:51:07\",\"data_checked_at\":\"2026-08-05 03:00:24\",\"availability_report_at\":\"2026-07-23 01:16:31\",\"recording_stats_at\":\"2026-09-02 11:32:37\",\"signal_defaults_at\":\"2026-09-02 12:06:26\"}","participants":13,"num_citations":7,"latest_version":"v1.0.0","zarr_verify_status":null,"zarr_verified_at":null,"owner_username":"nemarAdmin","owner_github":"nemarAdmin","file_size_formatted":"1021 GB","zarr_data_failures":null,"zarr_index_url":"https://zarr.nemar.org/on004024/zarr/index.json","attestation_deposit_type":null,"attestation_key_status":null,"attestation_deidentified":null,"attestation_no_duplicate":null,"attestation_upstream_source":null,"attestation_accepted_at":null}}