{"dataset":{"id":"51651","dataset_id":"on002799","name":"Human es-fMRI Resource: Concurrent deep-brain stimulation and whole-brain functional MRI","description":"This dataset comprises concurrent deep-brain electrical stimulation and whole-brain functional MRI data from 26 patients with medically refractory epilepsy. Patients underwent intracranial electrode implantation for clinical purposes, with one or multiple electrode contacts stimulated during fMRI acquisition using block design protocols. The resource includes anatomical imaging (T1, T2), resting-state fMRI, electrical stimulation-fMRI (es-fMRI) scans, field maps, electrode coordinates, and stimulation parameters, along with preprocessed derivatives.","owner_user_id":15,"status":"active","github_repo":"nemarDatasets/on002799","concept_doi":"10.82901/nemar.on002799","latest_version_doi":"10.82901/nemar.on002799.v1.0.0","created_at":"2026-06-21 11:01:01","updated_at":"2026-07-10 22:12:15","zenodo_concept_id":null,"is_sandbox":0,"visibility":"public","ezid_status":"public","enrichment_json":"{\n  \"version\": \"2.0\",\n  \"pipeline_stage\": \"validated\",\n  \"title\": \"Human es-fMRI Resource: Concurrent deep-brain stimulation and whole-brain functional MRI\",\n  \"description\": \"This dataset comprises concurrent deep-brain electrical stimulation and whole-brain functional MRI data from 26 patients with medically refractory epilepsy. Patients underwent intracranial electrode implantation for clinical purposes, with one or multiple electrode contacts stimulated during fMRI acquisition using block design protocols. The resource includes anatomical imaging (T1, T2), resting-state fMRI, electrical stimulation-fMRI (es-fMRI) scans, field maps, electrode coordinates, and stimulation parameters, along with preprocessed derivatives.\",\n  \"methods_description\": \"Data were collected from 26 human patients with surgically implanted intracranial electrodes in cortical and subcortical locations for medically refractory epilepsy. Electrical stimulation was applied to one or multiple electrode contacts during concurrent BOLD-fMRI acquisition using block design protocols. Data organization includes pre-operative (pre-implantation) and post-operative (post-implantation) sessions with anatomical scans, resting-state fMRI, es-fMRI scans, and associated field maps. Preprocessing was performed using fMRIprep and Freesurfer.\",\n  \"license\": \"CC0\",\n  \"dataset_type\": \"raw\",\n  \"authors\": {\n    \"Thompson WH*\": {},\n    \"Nair R*\": {},\n    \"Oya H*\": {},\n    \"Esteban O\": {},\n    \"Shine JM\": {},\n    \"Petkov CI\": {},\n    \"Poldrack RA\": {},\n    \"Howard M\": {},\n    \"Adolphs R†\": {},\n    \"*equally contributing, †corresponding author\": {}\n  },\n  \"keywords\": [\n    {\n      \"term\": \"fMRI\"\n    },\n    {\n      \"term\": \"deep brain stimulation\"\n    },\n    {\n      \"term\": \"intracranial electrodes\"\n    },\n    {\n      \"term\": \"Epilepsy\",\n      \"subject_scheme\": \"MeSH\",\n      \"value_uri\": \"http://id.nlm.nih.gov/mesh/D004827\"\n    },\n    {\n      \"term\": \"BOLD imaging\"\n    },\n    {\n      \"term\": \"neuroimaging\"\n    }\n  ],\n  \"related_identifiers\": [\n    {\n      \"identifier\": \"https://github.com/nemarDatasets/on002799\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"https://nemar.org/dataexplorer/detail?dataset_id=on002799\",\n      \"identifier_type\": \"URL\",\n      \"relation_type\": \"IsDescribedBy\"\n    },\n    {\n      \"identifier\": \"10.18112/openneuro.ds002799.v1.0.4\",\n      \"identifier_type\": \"DOI\",\n      \"relation_type\": \"IsDerivedFrom\"\n    }\n  ],\n  \"funding_references\": [\n    {\n      \"funder_name\": \"The Simons Foundation Collaboration on the Global Brain (RA)\"\n    },\n    {\n      \"funder_name\": \"UK Wellcome Trust (CIP) and European Research Council (CIP)\"\n    },\n    {\n      \"funder_name\": \"NIH\",\n      \"award_number\": \"U01NS103780\"\n    },\n    {\n      \"funder_name\": \"Simons Foundation\",\n      \"award_title\": \"Collaboration on the Global Brain\"\n    },\n    {\n      \"funder_name\": \"Knut and Alice Wallenberg Foundation\",\n      \"award_number\": \"2016.0473\"\n    },\n    {\n      \"funder_name\": \"Wellcome Trust\"\n    },\n    {\n      \"funder_name\": \"European Research Council\"\n    },\n    {\n      \"funder_name\": \"NIH\",\n      \"award_number\": \"R24MH117179\"\n    }\n  ],\n  \"resource_type_specific\": \"Structural MRI Dataset\",\n  \"modalities\": [\n    \"anat\",\n    \"func\",\n    \"ieeg\",\n    \"fmap\"\n  ],\n  \"sizes\": [\n    \"187.9 GB (12568 files)\"\n  ],\n  \"formats\": [\n    \".2mm/README\",\n    \".3d\",\n    \".H\",\n    \".K\",\n    \".README\",\n    \".annot\",\n    \".area\",\n    \".avg\",\n    \".avg_curv\",\n    \".avg_sulc\",\n    \".avg_thickness\",\n    \".bak\",\n    \".bib\",\n    \".cmd\",\n    \".crv\",\n    \".csv\",\n    \".ctab\",\n    \".curv\",\n    \".dat\",\n    \".dat~\",\n    \".defect_borders\",\n    \".defect_chull\",\n    \".defect_labels\",\n    \".done\",\n    \".env\",\n    \".flat\",\n    \".gii\",\n    \".gitattributes\",\n    \".gz\",\n    \".h5\",\n    \".hist\",\n    \".html\",\n    \".inflated\",\n    \".inflated_avg\",\n    \".inflated_pre\",\n    \".jacobian_white\",\n    \".json\",\n    \".label\",\n    \".left_right\",\n    \".local-copy\",\n    \".log\",\n    \".lta\",\n    \".m3z\",\n    \".md\",\n    \".mgh\",\n    \".mgz\",\n    \".mid\",\n    \".midthickness\",\n    \".mincost\",\n    \".mnc\",\n    \".nii\",\n    \".nofix\",\n    \".old\",\n    \".orig\",\n    \".orig_avg\",\n    \".param\",\n    \".pial\",\n    \".pial_avg\",\n    \".pial_semi_inflated\",\n    \".preaparc\",\n    \".reg\",\n    \".sharp\",\n    \".smoothwm\",\n    \".sphere\",\n    \".stats\",\n    \".sulc\",\n    \".sum\",\n    \".svg\",\n    \".temp\",\n    \".tex\",\n    \".thickness\",\n    \".touch\",\n    \".tsv\",\n    \".txt\",\n    \".volume\",\n    \".white\",\n    \".white_avg\",\n    \".xfm\",\n    \".yml\"\n  ],\n  \"source_hash\": \"f5b78f72847a02d13d0815d57bf53e4e80208a986b992f7be0aa0198578702d5\"\n}","last_activity_at":"2026-06-21 11:01:01","source":"openneuro","source_id":"ds002799","subject_count":26,"modalities":"anat,fmap,func,ieeg","age_min":13,"age_max":59,"file_size":188629838749,"total_files":16825,"tasks":"es,rest","metadata_columns_error":null,"staleness_warn_stage":null,"staleness_admin_notified_at":null,"authors":"Thompson WH*, Nair R*, Oya H*, Esteban O, Shine JM, Petkov CI, Poldrack RA, Howard M, Adolphs R†, *equally contributing, †corresponding author","license":"CC0","readme":"[![DOI](https://img.shields.io/badge/DOI-10.82901%2Fnemar.on002799-blue)](https://doi.org/10.82901/nemar.on002799)\n\nLink to published paper for this data resource: https://rdcu.be/b57kz\n\nThis collection contains data from 26 human patients who underwent electrical stimulation during functional magnetic resonance imaging (es-fMRI). The patients had medically refractory epilepsy requiring surgically implanted intracranial electrodes in cortical and subcortical locations. One or multiple contacts on these electrodes were stimulated while simultaneously recording BOLD-fMRI activity in a block design. Multiple runs exist for patients with different stimulation sites. \nData is organized in two sessions : Pre-op (pre electrode implantation) and Post-op (post electrode implantation). Raw data is provided in BIDS format and consists of T1s, T2s, resting state scans (pre-op), es-fMRI scans(post-op) , any associated field-maps and stimulation electrode coordinates and stimulation parameters. Pre-processed data (fMRIprep and Freesurfer) is present in the ‘derivatives’ folder.   \n\nNotes:\n1. Subject IDs 339, 369 and 394 do not have stimulation electrode location data available.\n2. Electrodes are in chA-chB format (chA gets leading positive phase of the stimulation). This information is stored in the \"channel\" file for each stimulation run.\n3. In some cases, two distant sites were stimulated simultaneously as indicated by the electrode listed under the appropriate run IDs within the ieeg folders.","bids_version":"1.0.0","sessions_count":2,"publish_date":null,"embedding_dirty":0,"license_tier":"public","zarr_status":"ready","zarr_converted_at":"2026-09-06 08:50:46","zarr_store_count":0,"zarr_index_etag":"ad0a6088a390e84bf7910422bb2b3d5b","zarr_source_commit":"0714ea6ee66554fbcbe6761dc492d29656412625","archive_status":null,"archive_size":null,"archive_retry_count":0,"records_status":"ready","archive_skip_reason":"dataset 175.7 GB exceeds 100.0 GB archive limit; use direct download","zarr_errors":0,"zarr_failure_count":0,"zarr_deterministic":0,"zarr_failed_at":null,"num_dataset_citations":8,"num_datapaper_citations":0,"n_channels":null,"electrode_system":null,"has_hed":0,"hed_version":null,"is_exemplar":0,"bytes_present":187913061711,"data_complete":1,"withdrawn_at":null,"withdrawn_reason":null,"archive_complete":null,"archive_absent_files":null,"archive_declared_files":null,"zarr_pool_breaks":0,"total_recording_duration":null,"recording_duration_min":null,"recording_duration_max":null,"recording_count":0,"recordings_unavailable":0,"recordings_measured":0,"channel_count_min":null,"channel_count_max":null,"sampling_frequency":null,"power_line_frequency":null,"eeg_reference":null,"placement_scheme":null,"sweep_stamps":"{\"enrichment_updated_at\":\"2026-06-21 11:35:25\",\"metadata_updated_at\":\"2026-06-21 11:35:35\",\"archive_checked_at\":\"2026-06-21 11:32:49\",\"zarr_checked_at\":null,\"records_checked_at\":\"2026-06-21 11:33:18\",\"citations_updated_at\":\"2026-08-17 03:00:58\",\"channel_montage_checked_at\":\"2026-06-28 23:08:43\",\"hed_checked_at\":\"2026-06-30 04:39:52\",\"data_checked_at\":\"2026-07-29 03:00:49\",\"availability_report_at\":\"2026-07-23 01:12:38\",\"signal_defaults_at\":\"2026-09-02 11:57:03\",\"recording_stats_at\":\"2026-09-07 03:00:59\"}","participants":26,"num_citations":8,"latest_version":"v1.0.0","zarr_verify_status":null,"zarr_verified_at":null,"owner_username":"nemarAdmin","owner_github":"nemarAdmin","file_size_formatted":"176 GB","zarr_data_failures":null,"zarr_index_url":"https://zarr.nemar.org/on002799/zarr/index.json","attestation_deposit_type":null,"attestation_key_status":null,"attestation_deidentified":null,"attestation_no_duplicate":null,"attestation_upstream_source":null,"attestation_accepted_at":null}}